By Amin J. Barakat, H. Gil Rushton
This complete, effortless to learn reference addresses the scientific implications of congenital anomalies of the kidney and urinary tract (CAKUT) in young children. Authored by way of a panel of across the world famous pediatric nephrologists and urologists, chapters speak about medical presentation, workup, interpretation of imaging reports, genetics, prenatal prognosis, prevention and remedy of assorted anomalies to aid the practitioner comprehend, diagnose and deal with CAKUT. Tables, figures, algorithms and an intensive appendix directory stipulations and syndromes linked to CAKUT are featured to aid physicians within the differential prognosis and workup of alternative conditions.
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Additional resources for Congenital Anomalies of the Kidney and Urinary Tract: Clinical Implications in Children
Nephron Clin Pract. 2013;125:127–38. 5. Puelles VG, Bertram JF. Counting glomeruli and podocytes: rationale and methodologies. Curr Opin Nephrol Hypertens. 2015;24:224–30. 6. Luyckx VA, Brenner BM. Birth weight, malnutrition and kidney-associated outcomes-a global concern. Nat Rev Nephrol. 2015;11:135–49. 7. Matsell DG, Cojocaru D, Matsell EW, Eddy AA. The impact of small kidneys. Pediatr Nephrol. 2015, 30:1501-9. 8. Potter EL. Normal and abnormal development of the kidney. ; 1972. 9. Hum S, Rymer C, Schaffer C, Bushnell D, Sims-Lucas S.
During the process of ascent, the kidney rotates medially 90° . The ascending kidney has a dynamic vascular supply during the course of its ascent, which drives from the adjacent common iliac or aortic segment. Progressively craniad aortic branches develop to supply the kidney at its current level, while more caudal branches regress . The persistence of caudal arterial branches results in multiple renal vessels. Anomalies of Number Situations in which there is congenital absence of renal tissue, either unilateral or, less commonly, bilateral, represent the most common anomalies of renal number.
Wolffian duct abnormalities, including congenital absence of the ipsilateral vas deferens, seminal vesicle, or epididymis, may occur in nearly 70 % of cases . Conversely, the incidence of unilateral renal agenesis in males with congenital absence of the vas deferens is only approximately 11 % if bilateral and 26 % if unilateral . Similarly, Müllerian duct anomalies are common in females with unilateral renal agenesis. During development of the female genital tract, the caudal portions of the Müllerian ducts fuse in the midline to give rise to the uterus and proximal two thirds of the vagina, while the more craniad portions remain unfused at the fallopian tubes.
Congenital Anomalies of the Kidney and Urinary Tract: Clinical Implications in Children by Amin J. Barakat, H. Gil Rushton