New PDF release: Aplastic Anemia: Pathophysiology and Treatment

By Hubert Schrezenmeier, Andrea Bacigalupo

ISBN-10: 0511017529

ISBN-13: 9780511017520

ISBN-10: 0521641012

ISBN-13: 9780521641012

This e-book takes account of the newest findings in laboratory examine and scientific trials to supply a entire and updated reference at the pathophysiology, epidemiology, prognosis and remedy of received and inherited aplastic anemia. in addition to supplying a close review of the pathophysiology of the ailment, the overseas workforce of authors covers all elements of administration, together with the verified techniques of bone marrow transplantation and immunosuppressive remedy, new techniques resembling using hematopoietic progress components and escalated immunosuppression, and arguable concerns equivalent to stem telephone transplantation. additionally integrated is a crucial foreign consensus rfile on remedy, and a last part concentrates at the inherited syndrome Fanconi's anemia. targeted therapy directions are given, making this the definitive source for hematologists and different clinicians focused on the administration and supportive care of sufferers with aplastic anemia. Scientists attracted to bone marrow failure also will locate this a useful reference.

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Extra info for Aplastic Anemia: Pathophysiology and Treatment

Example text

Hows, J. M. and Dexter, T. M. (1990) The hematopoietic defect in aplastic anemia assessed by long-term marrow culture. Blood, 76, 1748–57. Marsh, J. C. , Gibson, F. , Prue, R. , Dunn, V. , Hornkohl, A. , Nichol, J. L. and Gordon-Smith, E. C. (1996) Serum thrombopoietin levels in patients with aplastic anaemia. British Journal of Haematology, 95, 605–10. Martin, F. , Suggs, S. , Langley, K. , Lu, H. , Okino, K. , Morris, C. , McNiece, I. , Jacobsen, F. , Mendiaz, E. , Birkett, N. , Smith, K. , Johnson, M.

R. (1995) Lineage-restricted recruitment of immature haematopoietic cells in response to erythropoietin after normal haematopoietic cell transfection with erythropoietin receptor. Experimental Haematology, 23, 645. Metcalf, D. (1988) In The molecular control of blood cells. London: Harvard University Press. , Slanicka-Krieger, M. et al. (1995) Persistent growth impairment of bone marrow stroma after antilymphocyte globulin treatment for severe aplastic anaemia and its association with relapse. European Journal of Haematology, 5, 255–61.

Urabe, A. and Kato, T. (1996) A sensitive sandwich ELISA for measuring thrombopoietin in human serum: serum thrombopoietin levels in healthy volunteers and in patients with haematopoietic disorders. British Journal of Haematology, 93, 783–8. , Shimane, M. and Asano, H. (1993) The production of granulocyte colony-stimulating factor and interleukin-6 by human bone marrow stromal cells in aplastic anemia. Tohoku Journal of Experimental Medicine, 169, 325–32. , Zsebo, K. M. and Ogawa, M. (1991) Enhancement of murine blast cell colony formation in culture by recombinant rat stem cell factor, ligand for c-kit.

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Aplastic Anemia: Pathophysiology and Treatment by Hubert Schrezenmeier, Andrea Bacigalupo


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