By Togas Tulandi, Morrie Gelfand
The topic of androgen therapy in reproductive elderly men and women is attracting expanding curiosity from experts in replica medication, endocrinology and first care prone, in addition to from sufferers and the media.
The first e-book to hide androgen substitute in males and girls, Androgens and Reproductive Aging addresses the emotive issues of reproductive getting older, the menopause and using androgen vitamins to mitigate their results.
Edited by means of top professionals in reproductive medication and infertility, and boasting an all-star forged of authors, this accomplished textual content covers:
* androgen construction within the fit female and male
* the decline of androgen construction in the course of getting older, with the linked results on physique composition and libido
* the advantages and strength side-effects of androgen alternative therapy.
Ideal for quite a lot of clinicians and scientists drawn to reproductive getting older, the menopause, hormone alternative and androgen remedy, in addition to obstetricians, gynecologists and kinfolk practitioners, this detailed textual content is a hugely vital addition to literature within the area.
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Additional resources for Androgens and Reproductive Aging
Bilezikjian LM, Blount AL, Corrigan AZ, et al. Actions of activins, inhibins and follistatins: implications in anterior pituitary function. Clin Exp Pharmacol Physiol 2001; 28:244–248. 19. Burger HG, Dudley E, Mamers P et al. The ageing female reproductive axis I. Novartis Found Symp 2002; 242:161–171. 20. Judd HL, Judd GE, Lucas WE, Yen SSC. Endocrine function of the post-menopausal ovary. Concentrations of androgens and estrogens in ovarian and peripheral venous blood. J Clin Endocrinol Metab 1974; 39:1020–1024.
Safety data for long-term hormone replacement are also lacking. Ultimately one is left with some general conclusions: serum sex hormone levels decrease with age; the decline is likely due to age-related changes in both the gonads and the hypothalamus; the exact physiology of this interaction remains an area of great research interest both for its implications of male infertility and for decreasing age-related morbidity. Hormone changes in women Women, as opposed to men, have a defining marker of reproductive aging in the spontaneous, complete cessation of menstrual flow.
39 Despite these gains, there are few data showing that these replacement regimens improve overall functioning. Safety data for long-term hormone replacement are also lacking. Ultimately one is left with some general conclusions: serum sex hormone levels decrease with age; the decline is likely due to age-related changes in both the gonads and the hypothalamus; the exact physiology of this interaction remains an area of great research interest both for its implications of male infertility and for decreasing age-related morbidity.
Androgens and Reproductive Aging by Togas Tulandi, Morrie Gelfand